In the spring of 1962, Bishop Francis Green, then Bishop of Tucson, changed the boundaries of SS. Simon and Jude, St. Gregory and Most Holy Trinity parishes in Phoenix and established a new parish in Glendale to serve the growing population in the Northwest valley. Bishop Green placed the parish under the patronage of St. Louis, King of France to honor the early French missionaries of Arizona. Under the founding pastor, Father James McFadden, the Church and school buildings were completed and dedicated in 1964. Father McFadden served the parish for twenty years, building a spirit of community and lay participation in the areas of worship, community, service to others, and support. This spirit was fostered by succeeding pastors: Fathers Patrick Ratchford, Robert Kelly, Chuck Kiefer (Admin.), Richard Felt, and John Slobig. In July of 2004, Father Slobig was reassigned and Bishop Thomas Olmsted appointed a Canonical Pastor to serve the parish. Fathers Robert Skagen, Robert Clements, and Michael Diskin served the parishioners in this capacity. In July, 2012, Father Joseph Bui was appointed Parochial Administrator and became Pastor of St. Louis the King in July 2013.

St. Louis the King has been blessed with its parish organizations, its Religious Education program and a Catholic Elementary School which opened in 1965 staffed by the Sisters of Humility of Mary and dedicated lay teachers. When the Sisters left the parish and Bourgade Catholic High School in the early 1970’s, the convent building was converted to parish offices, religious education classrooms, and meeting rooms. A used portable building was installed at the school and converted to a library in 1994. In 2002 a new multi-purpose room and computer lab were constructed for the school, the first new building in forty years. A pre-school opened in 2006.

Because of changing demographics of the parish boundaries, a Mass in Spanish, ministry to Hispanics, and deacons to serve this growing population were added in 2005.

St. Louis the King parishioners continue to embrace their mission as a Eucharistic community, committed to growth in holiness and furthering the mission of Jesus Christ through worship, evangelization, formation and works of charity and social justice.